Viral Diversity Threshold for Adaptive Immunity in Prokaryotes

A recent paper concerning non-Darwinian (Lamarckian) evolution and mathematical modeling. From the abstract

Tracking this cost-benefit analysis across parameter space reveals viral mutation rate thresholds beyond which CRISPR-Cas cannot provide sufficient immunity and is purged from host populations. These results offer a simple, testable viral diversity hypothesis to explain why mesophilic bacteria disproportionately lack CRISPR-Cas immunity. More generally, fundamental limits on the adaptability of biological sensors (Lamarckian evolution) are predicted.

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About Artem Novozhilov

I am an applied mathematician interested in studying various evolutionary processes by means of mathematical models. More on my professional activities can be found on my page https://www.ndsu.edu/pubweb/~novozhil/
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